Iyo inozivikanwa kuti Covid-19 kunowedzera njodzi ye kumira kurova kwemoyo, sitiroko, uye Kureba Covid asi izvo zvaisazivikanwa ndezvekuti kukuvara kunoitika nekuti hutachiona hunokanganisa moyo pachayo, kana nekuda kwehurongwa kuzvimba kutangwa nekurwisa kwemuviri kuhutachiona. Muchidzidzo chitsva, vaongorori vakawana kuti hutachiona hweSARS-CoV-2 hwakawedzera huwandu hwemoyo macrophages uye zvakaita kuti vabve kubva kubasa ravo remazuva ese kuita kuzvimba. Iyo inoputika yemoyo macrophages inokuvadza iyo mwoyo nomuviri wose. Vatsvagiri vakawanawo kuti kuvharira mhinduro yekudzivirira nekudzivirira antibody mumuenzaniso wemhuka kwakamisa kuyerera kwemoyo wekuzvimba. macrophages uye yakachengetedzwa basa remwoyo rinoratidza nzira iyi ine simba rekurapa.
Zvinozivikanwa kuti COVID-19 inowedzera njodzi yekurohwa kwemoyo, sitiroko, uye Long COVID. Vanopfuura makumi mashanu muzana evanhu vanowana COVID-50 vanoona kuzvimba kana kukuvadzwa pamoyo. Izvo zvaisazivikanwa ndezvekuti kukuvara kwacho kunoitika nekuti hutachiona hunokanganisa moyo pachayo, kana nekuda kwekuzvimba kwehurongwa kunokonzerwa nemhinduro yekudzivirira kwemuviri kuhutachiona.
Chidzidzo chitsva chinovhenekera hukama pakati pekukuvara kwakakomba kwemapapu mune yakanyanya COVID-19 uye kuzvimba uko kunogona kutungamira kumatambudziko emwoyo. Chidzidzo chacho chakanangana nemasero ekudzivirira anonzi cardiac macrophages, ayo anowanzoita basa rinokosha pakuchengetedza hutano hwakanaka asi hunova hunovhiringidza mukupindura kukuvara kwakadai sekurwadziwa kwemoyo kana kukanganisa kwemoyo.
Vatsvagiri vakaongorora matishu emoyo kubva kuvarwere makumi maviri nevaviri vakafa kubva kuSARS-CoV-21-yakabatana acute respiratory distress syndrome (ARDS) ndokuzvienzanisa nemuenzaniso kubva kuvarwere makumi matatu nevatatu vakafa nezvikonzero zvisiri zveCOVID-2. Kutevera zvakaitika kune macrophages mushure mekutapukirwa, vaongorori vakatapurirawo makonzo SARS-CoV-2.
Zvakaonekwa kuti hutachiona hweSARS-CoV-2 hwakawedzera huwandu hwese hwemoyo macrophages muvanhu uye mbeva. Utachiona hwacho hwakakonzerawo kuti macrophages emwoyo ashanduke kubva pakushanda kwavo kwamazuva ose kuti ave kuzvimba. Iyo inoputika macrophages inokuvadza moyo uye nemuviri wese.
Chidzidzo chakagadzirwa mumakonzo kuti vaone kana mhinduro yavakaona yakaitika nekuti SARS-CoV-2 yaibaya moyo zvakananga, kana nekuti hutachiona hweSARS-CoV-2 mumapapu hwaive hwakasimba zvekupa moyo macrophages kuwedzera kuzvimba. Chidzidzo ichi chakatevedzera masaini ekuzvimba kwemapapu, asi pasina huvepo hwehutachiona chaihwo. Zvakaonekwa kuti kunyangwe pakashaikwa hutachiona, mbeva dzakaratidza mhinduro dzemuviri dzakasimba zvakakwana kuburitsa iyo moyo macrophage shanduko yakaonekwa vese muvarwere vakafa neCCIDID-19 uye mbeva dzakatapukirwa nehutachiona hweSARS-CoV-2. .
Hutachiona hweSARS-CoV-2 hunokanganisa zvakananga patishu yemapapu. Mushure me a Covid hutachiona, kunze kwekukuvadzwa kwakananga nehutachiona, immune system inogona kukuvadza dzimwe nhengo nekukonzera kuzvimba kwakasimba mumuviri wese.
Sezvineiwo, zvakaonekwawo kuti kuvharira immune system ne neutralizing antibody mumakonzo kwakamisa kuyerera kwekuzvimba kwemoyo macrophages uye kuchengetedza basa remoyo. Izvi zvinoratidza kuti nzira iyi (kureva. kudzvinyirira kuzvimba kunogona kuderedza matambudziko) ine mukana wekurapa kana ukawanikwa wakachengeteka uye unoshanda mumakiriniki ekuedzwa.
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References:
- NIH. Nhau dzinoburitswa - Hutachiona hwakanyanya hwemapapu panguva yeCOVID-19 hunogona kukonzera kukuvara kumoyo. Yakatumirwa 20 Kurume 2024. Inowanikwa pa https://www.nih.gov/news-events/news-releases/severe-lung-infection-during-covid-19-can-cause-damage-heart
- Grune J., and said 2024. Virus-Induced Acute Respiratory Distress Syndrome Inokonzera Cardiomyopathy Kuburikidza Nekukurudzira Mhinduro Dzinopisa Mumoyo. Kutenderera. 2024;0. Yakatanga kuburitswa 20 Kurume 2024. DOI: https://doi.org/10.1161/CIRCULATIONAHA.123.066433
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